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Food industry
Product testing,
selection and evaluation
Short-term in vitro experiments (metabolism, effect on the microbial community, stability in upper and lower intestine)
SHIME-experiments: short- and long-term evaluation of the intetinal fate of specific compounds or formulations
Absorption modeling(eg. Dialysis, Ultrafiltration or Caco2-cell cultures)
Host-microbe interaction studies using
attachment models
and
cell cultures
In vivo validation using animal models
Strain characterization
Proof-of-concept validation in human trials
Collaborative development of new innovative functional products (long term strategy)
Identification of active compounds or precursors
Isolation of microorganisms for biotechnological applications
Development of production startegies
Formulation of the end product
Pharmaceutical industry
Bioavailability and fate of active compounds
Dissolution studies
Permeability/absorption of active compounds
Stability in the upper GIT and microbial metabolism
Formulation development
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